Infectious and inflammatory diseases

Principle Investigator: Dr. K. Sundar, (Ph.D. Madurai Kamaraj University, 1992)

Post-doctoral Training and employment: SUNY Buffalo; Rutgers – NJ-Dental School, CUNY Medical School and Rutgers – NJ-Medical School, USA

Major Research Areas:

Immunomodulation of immune medicated diseases

Computational approaches for vaccine design

Drug target identification in pathogenic microbes using in silico approaches

Team Members

Full-time Doctoral Students:

Mr. M. Manikandan (ICMR Senior Research Fellowship)

Ms. M. Ajitha

Mr. R. Hari Balaganesh

Ms. M. Indhumathi

Part-time Doctoral Students:

Mr. R. Kasimani

Mr. G. Vinothapooshan

Mr. N.R. Livingston Raja

Ms. J. Christina Rosy

Selected Publications of the PI: (H-index=11)

Livingston Raja,N. R. and K. Sundar (2012) Psidium guajava confers gastro protective effects on rats. Eur. Rev. Med. Pharm. Sci. 16:151-156.

Liu, Q., K. Sundar, P.K. Mishra, G. Mousavi, Z. Liu, A. Gaydo, F. Alem, D. Lagunoff, D. Bleich, W.C.Gause (2009) Helminth infection can reduce insulitis and type 1 diabetes through CD25- and IL-10-independent mechanisms. Infect. Immun. 77(12): 5347-58.

Sundar, K., A. Boesen and R. Coico (2007) Computational prediction and Identification of HLA-A2.1-specific Ebola virus CTL epitopes. Virology 360: 257-63.

Woods, C.C., K. Sundar, C. Tessler, T.W. Lebsack, L. Grainger, A. Nielsen, D. Bleichand D. DeLuca (2006) Tissue inhibitor of metalloproteinase-2 Inhibits T-cell infiltration and preserves pancreatic β-cell function in an in vitro type 1 diabetes mellitus model. J. Autoimmunity. 27(1):28-37.

Sundar, K., S. Jacques, P. Gottlieb, R. Villars, M.E. Bennito, D.K. Taylor and L.A. Spatz (2004) Expression of Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies. J. Autoimmunity 23(2):127-140.